Thattathin Marayathu is the second film directed by Vineeth Sreenivasan after 'Malarvadi Arts Club' (2010). The film is about Vinod, a Hindu youth who falls in love with Ayisha, a Muslim girl who happens to be the daughter of a local politician. Thattathin Marayathu tells their love story in the midst of student politics, local gangs, etc. Nivin Pauly who had made his debut through Vineeth's 'Malarvadi' plays the role of Vineeth and debutant Isha Talwar plays Ayisha. Aju Varghese plays the role of 'Kuttu'.