10 Enradhukulla, directed by Vijay Milton and produced by AR Murugadoss features Vikram and Samantha in the lead roles. Vikram, a hire driver does anything for money. He gets an assignment to drive a car from Chennai to Mussoorie. After starting his drive, he finds Samantha trapped in his car. Who is Samantha and why Vikram was asked to drive the car with her forms the base of the story.