The story revolves around Gautham (Mahesh Babu) who is diagnosed with an integration disorder having 25% less grey matter in his brain. He imagines himself in mysterious situations that tend to leave him disturbed at times. During this he comes in contact with a few people who help him solve these issues. Providing him ample support is Sameera (Kriti Sanon) who is a TV journalist. How Gautham overcomes his mental disorder and solves the mystery surrounding him forms the remaining part of the story.